Connecting Vitamin C to Cardiovascular Health

Connecting Vitamin C to Cardiovascular Health

Learn how low levels of vitamin C can affect heart health. Antioxidant activity, supporting healthy vascular smooth muscle cells, healthy collagen production and healthy lipid profiles are just some of the ways vitamin C supports cardiovascular health.

The scientific literature is clear: low levels of vitamin C can affect heart health. Vitamin C supports heart health via several important mechanisms:

Insufficient vitamin C levels leads to weakened blood vessel walls which trigger a biological repair process leading to plaque formation.

In an interview featured in Element magazine, naturopathic cardiologist Daniel Chong, ND explains research on this connection:

“The idea that vitamin C may be a key component in cardiovascular health was first conceptualized by Linus Pauling and Matthias Rath in 1990. Humans are one of the few animals on the planet that are unable to make vitamin C. They are also one of the few animals to develop cardiovascular disease. The only animals that have heart attacks like we do are guinea pigs, and they don’t make vitamin C either.”

Chong continues: “Vitamin C is required for collagen production. Pauling and Rath suggested that vitamin C insufficiency weakens blood vessel walls which triggers a biological repair process leading to plaque formation. They noticed that one of the most effective repair molecules to be mobilized during the process was lipoprotein(a) [Lp(a)]. They observed an inverse relationship between production of Lp(a) and vitamin C levels, and proposed that Lp(a) might act as a surrogate to protect the blood vessels when vitamin C levels decline.”

The Dr. Rath Research Institute then developed a mouse model to imitate human metabolism. The mice were genetically altered to lose the ability to produce vitamin C and at the same time gain the ability to produce Lp(a). Mice were placed on a consistent diet with varied amounts of vitamin C (in the form of ascorbic acid).”

The study results showed that mice consuming less vitamin C produced more Lp(a). Also, the production of Lp(a) paralleled the development of atherogenic plaques. Even more exciting is that the researchers were able to achieve a level of vitamin C where the mice had no plaque formation at all.”

Vitamin C is a nutrient vital to human health. As integrative practitioners know, determining how much vitamin C to recommend can be highly individualized, based on a person’s age and health status. “I don’t feel many of the human studies of vitamin C supplementation have been useful in estimating the amount that’s sufficient to support cardiovascular health because they rarely use dosages of more than 1,000 mg per day,” explains Chong. He says this is inconsistent when compared to amounts produced endogenously in animals. “For example, goats produce a baseline amount of vitamin C of a few thousand milligrams per day when they’re healthy and not under stress,” says Chong. “Interestingly, when they are exposed to stress of any kind, goats increase production of vitamin C to over 10,000 mg per day.”

All experts agree that when taking vitamin C, regardless of the dose recommended, it’s always best to consume multiple doses throughout the day versus one large daily dose. This mimics nature, says Chong, who often recommends 2,000 mg per day. “Some patients may need more, depending on their diet and lifestyle,” says Chong.

Article published by By Emerson Ecologics | Feb 11, 2021

Toilet Paper- the key to preventing COVID-19

Toilet Paper- the key to preventing COVID-19

So, the COVID-19 coronavirus is most likely going to be in your community in the next few weeks if it isn’t already and I am repeatedly being asked by patients what they can do to protect their families besides stocking up on toilet paper. 

The biggest thing that we can do for our families and ourselves is boost innate immunity against viruses; do things to help prime our immune system so it is ready to shut the virus down.  There is no need to panic- for most people it will be a mild illness and so the very same measures that we take against a flu can help with respect to immune building for the coronavirus.  I have to start by saying make sure you are doing the basics- good nutrition (largely plant based whole foods diet), good sleep (try to get 7-9 hours of uninterrupted sleep a night), decrease stress (meditate, laugh, be social), exercise, and wash hands regularly.  All of these things seem so basic, but really do affect the health of our immune system.

Now that that is out of the way- what else can you do naturally?  This is kind of an easy one for me because I have used it for so long with my own family, friends and patients and I know that it works.  There are a few ingredients that have many good studies and medical literature supporting the fact that they can measurably increase our immune system efficacy against viruses.  It specifically works by increasing the potency of our Natural Killer Cells, which besides having an awesome name, are one of our biggest defenses against viruses. Although I make an antiviral cocktail from different supplements that I keep in my fridge when my family is sick; the one ingredient that always goes in is the Immunoberry liquid by Designs For Health.  It is a one stop shop of the studied powerhouse antiviral ingredients; Elderberry, Astralagus, Cherry Bark, Maitake and Shitake mushrooms, and Beta Glucans.   

My kids even ask for “the mushroom stuff” when they are starting to feel under the weather or are sick.  I believe everyone should keep a bottle of this in their fridge. You should check with your physician, however this supplement is generally very safe for children as well as adults and very easy to take  -about one ml (one dropper full) every day when you are sick or getting sick to boost your natural immunity.  Although, you could use it every day – I don’t recommend that because if you are otherwise healthy you don’t need an immunity boost every day. The taste is “earthy” and for those who don’t like eating dirt it can easily be masked in another liquid.  (Read: you can get your kids to take it).

You can find it in our shop for much cheaper than you will find anywhere else.  One bottle lasts my family of six 4 months.  Any supplement in our shop is quality checked and you can be certain that you are getting what you paid for.  We really want our patients to afford and use the supplements that matter so we tried to pass on as big of a discount as we can to you.  Please forward this along to anyone else who you think might benefit from this information.  I will include the studies below if anyone wants to do some light reading. 

If you are convinced here is a link to our shop: If you have already registered with us just sign in, otherwise it only takes a minute to create an account and you can have access to all of our quality tested supplements.

If the link doesn’t work you can visit our site at and click Shop.

Beta-glucan recognition by the innate immune system.

Goodridge HS, Wolf AJ, Underhill DM.

Immunol Rev. 2009 Jul;230(1):38-50. doi: 10.1111/j.1600-065X.2009.00793.x. Review.

Antimicrobial properties of shiitake mushrooms (Lentinula edodes).

Rao JR, Smyth TJ, Millar BC, Moore JE.

Int J Antimicrob Agents. 2009 Jun;33(6):591-2. doi: 10.1016/j.ijantimicag.2008.10.018. Epub 2008 Dec 31. No abstract available. Erratum in: Int J Antimicrob Agents. 2009 Jun;33(6):597. Smyth, T J [added].

beta-Glucans and dectin-1.

Tsoni SV, Brown GD.

Ann N Y Acad Sci. 2008 Nov;1143:45-60. doi: 10.1196/annals.1443.019. Review.

Medicinal importance of fungal beta-(1–>3), (1–>6)-glucans.

Chen J, Seviour R.

Mycol Res. 2007 Jun;111(Pt 6):635-52. Epub 2007 Mar 7. Review.

 Colds and influenza: a review of diagnosis and conventional, botanical, and nutritional considerations.

Roxas M, Jurenka J.

Altern Med Rev. 2007 Mar;12(1):25-48. Review.

Inhibition of proinflammatory activities of major periodontal pathogens by aqueous extracts from elder flower (Sambucus nigra).

Harokopakis E, Albzreh MH, Haase EM, Scannapieco FA, Hajishengallis G.

J Periodontol. 2006 Feb;77(2):271-9.

Immunomodulatory and antimicrobial effects of some traditional chinese medicinal herbs: a review.

Tan BK, Vanitha J.

Curr Med Chem. 2004 Jun;11(11):1423-30. Review.

Fungal beta-glucans and mammalian immunity.

Brown GD, Gordon S.

Immunity. 2003 Sep;19(3):311-5. Review.

Effects of D-Fraction, a polysaccharide from Grifola frondosa on tumor growth involve activation of NK cells.

Kodama N, Komuta K, Sakai N, Nanba H.

Biol Pharm Bull. 2002 Dec;25(12):1647-50.

Anti-angiogenic property of edible berries.

Roy S, Khanna S, Alessio HM, Vider J, Bagchi D, Bagchi M, Sen CK.

Free Radic Res. 2002 Sep;36(9):1023-31.

[Studies on pharmacological junctions of hairy root of Astragalus membranaceus].

Jin R, Zhang X, Chen C, Sun Z, Shen Y, Liu D, Hu Z.

Zhongguo Zhong Yao Za Zhi. 1999 Oct;24(10):619-21, 639. Chinese.

Addition of Maitake D-fraction reduces the effective dosage of vancomycin for the treatment of Listeria-infected mice.

Kodama N, Yamada M, Nanba H.

Jpn J Pharmacol. 2001 Dec;87(4):327-32.

Increased production of antigen-specific immunoglobulins G and M following in vivo treatment with the medicinal plants Echinacea angustifolia and Hydrastis canadensis.

Rehman J, Dillow JM, Carter SM, Chou J, Le B, Maisel AS.

Immunol Lett. 1999 Jun 1;68(2-3):391-5.

Anthocyanins are detected in human plasma after oral administration of an elderberry extract.

Cao G, Prior RL.

Clin Chem. 1999 Apr;45(4):574-6. No abstract available.

Interaction of vitamin C and flavonoids in elderberry (Sambucus nigra L.) during juice processing.

Kaack K, Austed T.

Plant Foods Hum Nutr. 1998;52(3):187-98.

Induction of immunomodulating cytokines by a new polysaccharide-peptide complex from culture mycelia of Lentinus edodes.

Liu M, Li J, Kong F, Lin J, Gao Y.

Immunopharmacology. 1998 Nov;40(3):187-98.

Chinese herbs: a clinical review of Astragalus, Ligusticum, and Schizandrae.

Sinclair S.

Altern Med Rev. 1998 Oct;3(5):338-44. Review.

The function of human NK cells is enhanced by beta-glucan, a ligand of CR3 (CD11b/CD18).

Di Renzo L, Yefenof E, Klein E.

Eur J Immunol. 1991 Jul;21(7):1755-8.